Teaching Cases

ASH Teaching Cases emphasize standard approaches to classic hematologic problems and are designed to simulate the steps involved in diagnosing a patient, from taking the history and performing a physical exam, to ordering and interpreting lab tests, to making a final diagnosis and following the clinical course of the disease. While working through each case, learners are challenged to consider the right questions to ask at each step in the process. Each case includes a set of teaching points and a bibliography with links to references. To keep track of your progress in cases you’ve started, view all cases in progress in My Dashboard.

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Category II: Bone Marrow Disorders

II-1 - Macrocytosis

Emmanuel C. Besa, MD

A 78-year-old woman is being seen by her physician due to a macrocytosis of her red cell indices. She complains of feeling tired during the day and of sleeping more than she did in the past.

II-2 - Polycythemia

Virginia C. Broudy, MD

A 72-year-old man presents for evaluation of polycythemia.

II-3 - Fever and Petechial in an Infant

James Harper, MD

A 17-month-old boy was admitted to the hospital with a two-week history of fever (T max 104º F) and a two-day history of rash on his legs.

II-4 - Cough, Back Pain, and Fatigue

Robert A. Kyle, MD, and Michael Tomasson, MD

A 65-year-old woman experiences a sudden onset of fever, shaking chills and productive cough. She has had progressive fatigue for six months and lower back pain for several years.

II-5 - Unexplained Leukocytosis in an Adult

Eileen Scigliano, MD

A 50-year-old man presents with a two-month history of fatigue and early satiety.

II-6 - A Patient with Pancytopenia

Peter W. Marks, MD

A 34-year-old woman is referred to the emergency department after seeing her dentist for bleeding gums and is found to have pancytopenia.

II-7 - Fatigue, Dyspnea, and Abnormal Blood Counts

Katherine Walsh, MD and Eric Kraut, MD

A 45-year-old woman presents with complaints of marked fatigue and progressive dyspnea on exertion.

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